The Liver Cancer Program (LCP) conducts clinical trials for patients with many different types of liver cancer, including hepatocellular carcinoma and cholangiocarcinoma.
Liver Cancer Program
A multidisciplinary network of researchers and clinicians dedicated to improving early detection, diagnosis, prognosis and treatment of liver cancer.
New Discoveries
Learn about our most recently published research.
Seminar Series
Dr. Praveen Sethupathy, PhD. "Single-Cell Analysis Reveals Rewired Cell-to-Cell Communication Patterns and Unique Dependencies in Fibrolamellar Carcinoma” April 22, 2024, 1 p.m. EST
Liver Cancer Program
About
The mission of the NCI-CCR-LCP is to develop a multi-disciplinary program focused on the prevention, early detection, improved diagnosis and treatment of liver cancer. Liver cancer is the 3rd most common cause of cancer-related death worldwide.
In the United States, liver cancer is the 5th most common cause of cancer-related death and is one of the few cancers with rising incidence and mortality, with 40,000 new cases of liver cancer diagnosed per year. Health disparity in liver cancer is evident including a significantly higher mortality in minorities, higher incidence among men and higher prevalence in Asia and Africa. Liver cancer remains a difficult-to treat disease with sub-optimal patient diagnosis and poor patient survival mainly due to the lack of screening tools, advanced stage of tumors at diagnosis, and the lack of approved novel therapies.
To address these dire concerns, the NCI-CCR-LCP will consolidate expertise and create an interactive and collaborative environment to foster liver cancer care and research through innovative laboratory studies and promising clinical applications, such as molecular subgrouping of patients and biomarker-guided molecularly-targeted therapies.
Our multidisciplinary research and clinical team will apply a transdisciplinary approach with integration of research and clinical expertise to improve the diagnosis, prognosis, treatment and outcome of patients with liver disease and cancer.
Researchers
One of the central aims of the NCI-CCR-LCP is to foster collaborations between intramural and extramural investigators with an interest in liver cancer research. We plan to initiate and support these collaborations at every level.
Team
Leadership
Program Staff
Team Members and Advisory Board
Our team members include clinical, basic, and translational researchers from the Center for Cancer Research (CCR), the Division of Cancer Epidemiology and Genetics (DCEG), and the Center for Global Health at the National Cancer Institute (NCI); the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) and the NIH Clinical Center.
Our Advisory Board members are from the extramural cancer research community.
News
Seminars
All seminars are virtual.
Visit our archives page to learn more about seminars from previous years.
Recorded seminars are available below and on our YouTube Playlist as part of NCI YouTube.
2024
Spring 2024
April 22 Praveen Sethupathy, PhD, Professor, Cornell University (1pm EST)
"Single-Cell Analysis Reveals Rewired Cell-to-Cell Communication Patterns and Unique Dependencies in Fibrolamellar Carcinoma"
https://nih.zoomgov.com/j/1606886958?pwd=bWpiSER6VWpqY2ZQL2ltaThnU0hTUT09
Meeting ID: 160 688 6958; Passcode: 849963
May 16 Hien Dang, PhD, Assistant Professor and Vice Chair, Thomas Jefferson University (1pm EST)
Fall 2024
September 12 Ghassan Abou Alfa, Professor, Memorial Sloan Kettering Cancer Center (1pm EST)
October 7 Chiara Braconi, M.D., Ph.D., Professor, University of Glasgow (9am EST)
November 18 Hongyang Wang, MD, Professor and Director, National Center for Liver Cancer, China (9am EST)
Previous Seminars
2024 Seminars
March 18 Valerie Chew, PhD, Assistant Professor, SingHealth Duke-NUS
February 26 Amit Singal, MD, Professor, UT Southwestern
January 29 Lopa Mishra, MD, Professor and Chair, Feinstein Institute for Medical Research and Cold Spring Harbor Laboratory
2023 Seminars
December 14 Scott Friedman, MD, Professor and Chief, Mount Sinai, New York
November 13 Giorgio Trinchieri, MD, Senior Investigator and Chief, Laboratory of Integrative Cancer Immunology, NCI, NIH
October 19 Irene Ng, MD, PhD, Chair and Professor, The University of Hong Kong
September 21 Mitesh Borad, MD, Professor, Mayo Clinic
June 12 Anna Mae Diehl, MD, Professor, Duke University
May 18 David Brenner, MD, President and Chief Executive Officer of Medicine, Sanford Burnham Prebys, San Diego (La Jolla), CA
Liver Fibrosis and Hepatocellular Carcinoma
March 30 Stephanie Ma, PhD, Associate Professor, The University of Hong Kong
February 23 Hashem B. El-Serag, MD, MPH, Professor, Baylor College of Medicine
January 12 Anna Suk-Fong Lok, MD, Assistant Dean, University of Michigan Medical School
2022 Seminars
December 1 Mathais Heikenwälder, PhD, Professor, German Cancer Research Center, Germany
November 17 Sanford Simon, PhD,The Gunter Blobel Professor, The Rockefeller University, NY
October 17 Bruno Sangro, MD,Professor, University of Navarra, Spain
September 22 Augusto Villanueva, MD, PhD, Associate Professor, Mount Sinai
June 13 Jessica Zucman-Rossi MD, PhD, Professor, University Paris Descartes, France
Mechanisms of Liver Carcinogenesis Across a Lifetime
May 19 Robert Schwabe, MD, PhD Professor, Columbia University
The Role of Hepatic Stellate Cells in Liver Cancer
April 28 Josep M. Llovet, MD, Professor, Mount Sinai, NY and University or Barcelona, Spain
March 31 Ignacio Melero Bermejo, MD, PhD, Professor, University of Navarra, Spain
New Waves of CD137(4-1BB) Based Immunotherapies
February 15 Helen Reeves, MD, PhD, Professor, Newcastle University, UK
January 13 Mark Yarchoan, MD, Assistant Professor, Johns Hopkins University
Contact
For questions about patient care or clinical trials
Please contact Donna Mabry, MS, CRNP
240-858-3155 | donna.mabry@nih.gov
For questions about our research program
Please contact Anuradha S. Budhu, Ph.D.
240-760-6837 | budhua@mail.nih.gov